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SuperConvection™ is a new
technology that speeds up thermal cycling
and increases temperature homogenization.
The beneficial effects of SuperConvection
on PCR temperature ramping and homogenization
have been scientifically evaluated and published
in the
European Biophysics Journal as
well as
Biotechniques.
AlphaHelix has developed,
AmpXpress,
a new instrument for rapid and high-quality
PCR based on SuperConvection.
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SuperConvection is a technology that
increases the temperature homogenization
rate during heating and cooling, thereby
enabling very rapid thermal cycling in e.g.
PCR. SuperConvection enables a much faster
PCR run in any sample volume from 20 up
to 200 µL and therefore provides a higher
detection
sensitivity than any other qPCR platform.
Typical applications
range from clinical and veterinary diagnostics;
forensic science; and food and biosafety
testing. |
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Features of SuperConvection
Thermal heterogeneity is
the rate limiting factor in thermal
cycling processes. It is also the
major source of non-specific amplification.
SuperConvection induces enhanced
mass transport in the reaction mixture.
This has two effects:
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Instantaneous thermal
homogenisation. |
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Enhanced reaction kinetics. |
Read more about SuperConvection. |
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