SuperConvection™

SuperConvection™ is a new technology that speeds up thermal cycling and increases temperature homogenization. The beneficial effects of SuperConvection on PCR temperature ramping and homogenization have been scientifically evaluated and published in the European Biophysics Journal as well as Biotechniques.

AlphaHelix has developed AmpXpress, a new instrument for rapid and high-quality PCR based on SuperConvection.

SuperConvection enables a much faster PCR run in any sample volume from 20 up to 100 µL and therefore provides a higher detection sensitivity than any other PCR platform.

Typical applications range from clinical and veterinary diagnostics, forensic science, and food and biosafety testing.

Features of SuperConvection

Thermal heterogeneity is the rate limiting factor in thermal cycling processes. It is also the major source of non-specific amplification.

SuperConvection induces enhanced mass transport in the reaction mixture. This has two effects:

• Instantaneous thermal homogenisation.
• Enhanced reaction kinetics.

Read more about SuperConvection (pdf)